Thursday, July 4, 2013

About 20-Hydroxyecdysone and Total Ecdysterones




20-Hydroxyecdysone and Total Ecdysterones is extracted from natural plant Cyanotis vaga . The main composition is 20-Hydroxyecdysone and Total Ecdysterones.
20-Hydroxyecdysone and Total Ecdysterones is nice and good.

Properties:
1. Appearance: Light yellow to white Crystal powder.
2. Formula: C27H44ON. (N=6-8)
3. Extract solvents: Alcohol.
4. Product particle size is 80.

ITEMS INDICES :
Appearance Light yellow to white Crystal powder.
Drying Weightlessness; 5.0% Max.
Ash; 2% Max.
20-Hydroxy Ecdysterone 50-95% (HPLC)
Total Ecdysterone 70-95% (HPLC)
Technological Process:
Raw Material -- Immersed in water -- Filtered -- Concentrated in Vacuum -- Subsidence in Alcohol -- Filtered -- Concentrated in Vacuum -- Kill of Bacteria -- Dry -- Powder



More about:natural 20-Hydroxyecdysone and Total Ecdysterones for sale
From:Natural Food Colors

Tuesday, July 2, 2013

About Corn Color



Zeaxanthin(Corn Color) is a natural fat-soluble pigments, soluble in ether, acetone, petroleum ether, esters and other organic solvents; zeaxanthin 1% solution of lemon yellow, 10 ℃ above blood red oily liquid, 10 ℃ the following as a yellow semi-solid oil; has good resistance to oxygen, acid resistance; HTST treatment basically stable, long is unstable; temperature is relatively stable; stability of Fe and Al poor, but for other ions, acid, alkali and a reducing agent such as Na2SO3 stable; present in the solid food zeaxanthin, at room temperature and stable under natural light conditions, a 1% solution of the more sensitive to sunlight.
Zeaxanthin has a molecular structure itself, so that zeaxanthin has a strong antioxidant activity, zeaxanthin exists in the molecular structure of 11 conjugated double bonds, forming a large conjugated system, these conjugated key makes the existence of zeaxanthin can block free radical chain transfer, which has a strong antioxidant activity. Zeaxanthin in the organism by reducing the chemical activity of substances such as singlet oxygen free radicals and photochemical reactivity of sensitivity to play against oxidation. While zeaxanthin molecular structure on the tail with a hydroxyl group, enhancing its antioxidant capacity to protect the biological system from a number of processes or due to excessive oxidation reaction of the potential harmful effects of
Antioxidant zeaxanthin oxidative damage and antioxidant protection due to the imbalance caused by the metabolism of free radicals that can cause many diseases such as cardiovascular, cancer, aging, inflammation, cataract, and a series of nervous system diseases. As early as 30 years ago, researchers discovered that β-carotene with singlet oxygen quenching ability. With ongoing research, it was found that not only the β-carotene has antioxidant ability, most carotenoids have antioxidant capacity. Carotenoids chemical structure and their antioxidant activity is closely related to, oxidation activity depends on the molecular structure of the conjugated double bonds in the number and structure of the end groups. Zeaxanthin molecule has 11 conjugated double bond and a hydroxyl group on the end of a group, this structure so that they have a strong antioxidant capacity. In vivo, zeaxanthin although it is not converted to vitamin A, vitamin A activity that does not have, but it is important to the human body can use powerful antioxidant by quenching singlet oxygen free radical scavenging antioxidant such acts to protect the body tissues cells in order to reduce the risk of certain diseases.



More about:Corn Color suppliers for sale
From:Natural Food Colors

Sunday, June 30, 2013

About Natural Carotenes




Carrots contain large amounts of β-carotene intake human digestive system, it can be converted into vitamin A, is currently the most secure vitamin A products (simple supplement chemical synthesis of vitamin A, excessive make people poisoned). It can maintain the health of the eyes and skin, improve night blindness, rough skin condition, helps the body from free radical damage. Not with vinegar and acidic substances while taking.

So far, has at least 600 or more kinds of natural carotenoids (Natural Carotenes) discovered by us, of which a small part (such as β-carotene) in the body is converted to vitamin A. As we know, squash and carrot except β-carotene, but also contains a lot of α-carotene.

Need the crowd:
A long-term malabsorption of fat, such as suffering from digestive diseases, gastrointestinal partial resection, often lead
Caused by lack of vitamin A. This situation often occurs in children under 5 years of age who, mainly because of inadequate intake of vitamin A causes.
2, vitamin A for long-term wear contact lenses or a long time watching the computer screen of the people, it is important nutrients.
3, pregnant and lactating women also need vitamin A.

Role and Function:
1, to maintain the integrity of skin and mucous layer, to prevent dry skin, rough;
2, visual cells constituting the photosensitive materials;
3, to promote growth and development, effective health promotion and cell development, prevent deficiencies. To promote the healthy growth of bones and teeth;
4, maintaining reproductive function;
5, maintain and promote immune function. Data presentation, carrots with the prevention and suppression of lung function. Carrots contain carotene into the body, will be converted into vitamin A. Each molecule can be transformed into carrot 2 vitamin A molecules.

Metabolism and absorption:
Vitamin A and carotene absorption process is different. Absorption of vitamin A is active absorption, requires energy, absorption rate 7-30 times faster than carotene. The absorption of carotenoids for the physical diffusion, absorption and intake somehow related. Carotene absorption site in the small intestine, small intestine cells containing carotene dioxygenase, in its role of carotenoids into intestinal cells is broken down into retinal or retinol.

More about:Natural Carotenes for sale
From:Natural Food Colors

Friday, June 28, 2013

About Tartrazine




Tartrazine is a water-soluble synthetic pigment, bright bright yellow, monochrome varieties. The amount of lemon can be safely used in food, beverage, pharmaceutical, cosmetics, beverages, tobacco, toys, food packaging materials, such as coloring. China allows the use of synthetic pigment amaranth, carmine, tartrazine, sunset yellow and indigo. They are used for fruit water, fruit powder, fruit syrup, soft drinks, liqueur, red and green silk, canned food, as well as on the surface color and other pastries. These synthetic pigment indeed the food surface dressed exceptionally likable, however, they are banned for the following foods: meat and processed products (including offal processed products), fish and processed products, fruits and products (including juices , preserved fruits, jams, jellies and brewing wine, spices, baby food, biscuits and so on.
Edible factors

The reason why I can do the Food and Drug tartrazine dye, because it is a relatively high degree of safety, non-toxic, not piling up the body, most of the prototype excreted, a small amount via metabolism, its metabolites without toxic effects on human . And it is used in the production of raw materials for the amino acid, tartaric acid and two - naphthol-6 - sulfonic acid are substantially non-toxic substances. Therefore, the World Organization (FAO) and the World Health Organization (WHO) in 1994 gave it a very forgiving daily intake amount promised. If you use the standard lemon, then enter the amount of the body away from the daily intake amount promised a lot of difference.
Purpose:
Azo-type acid dyes. Mainly used in food, beverage, pharmaceutical and cosmetics coloring, but also for wool, silk dyeing and manufacturing color lakes. Water-soluble synthetic colors, bright bright yellow, widely used in ice cream, ice cream, jelly, yogurt, beverages, canned food, candy coating and other coloring. According to China's "food additives health standards" (GB2760-1996) provides that: for high-sugar juice (flavored) or fruit juice (flavored) or fruit juice (flavored) drinks, carbonated beverages, liqueur, candy, cakes loaded on the color, watermelon canned sauce, plum, shrimp (flavored) tablets, stains made dishes, red and green silk, the maximum usage 0.1g/kg; for ice cream, the maximum usage 0.02g/kg. For plant protein drinks, lactic acid bacteria beverages, the maximum amount 0.05g/kg.

More about:Tartrazine sales for sale
From:Natural Food Colors

Wednesday, June 26, 2013

What is emulsified lycopene?



Name:emulsified lycopene
Lycopene is a natural plant pigment contained. Mainly in the Solanaceae plant tomatoes ripe fruit. It is present in nature is found in plants of the strongest antioxidant. Scientifically proven that the human body singlet oxygen and oxygen radicals against the body's own immune system is the culprit. Lycopene radical scavenging effect better than other carotenoids and vitamin E, which quenching rate constants of singlet oxygen is vitamin E 100 times. It can effectively control due to aging, decreased immunity caused by various diseases. Therefore, it is subject to the concern of experts around the world.

Lycopene (lycopene) is the main pigment ripe tomato, which is not oxygenated carotenoids. 1873 Hartsen for the first time from the berries yam TamuscommunisL. Separating the red crystal. 1913 Schunk found that this substance and carotene are different, its first named lycopene, still in use. Its molecular formula is C40H56, a molecular weight of 536.85, pure dark red needle-like crystals, the molecular structure has 11 conjugated double bonds and two non-conjugated double bonds consisting of straight-chain hydrocarbons. In carotenoids, it has the highest antioxidant activity. The free radical scavenging effect of lycopene better than other carotenoids and vitamin E, which singlet oxygen quenching rate constant of vitamin E is 100 times that found in nature so far the strongest antioxidants. For a long time, lycopene has been used as a common plant pigment, did not attract too much attention.

Physical and chemical properties
2.1 Stability
Because lycopene molecule has 11 conjugated double bonds and two non-conjugated double bonds, making the relatively poor stability of lycopene, can occur under certain conditions, cis-trans isomerization and oxidative degradation. Lycopene is sensitive to oxidation reaction, the solution after 12 hours after exposure to the sun, which is essentially wiped lycopene. Solution Fe3 + and Cu2 + would lycopene oxidation catalytic effect of light, while the other metal ions such as K +, Mg2 +, Ca2 +, Zn2 +, etc. are little influence, so natural lycopene extraction and application process should try to avoid the use of iron and copper containers. pH on lycopene also have an impact, when dissolved in ethanol lycopene, and modulated into a pH value of from 1 to 14, the results indicate that lycopene is unstable to acid, alkali is relatively stable, the use of lycopene as a pigment Time is not suitable for acidic beverages. Thus, the factors affecting the stability of lycopene oxygen, light, metal ions and pH, the lycopene extraction, storage, processing and analysis should be in the control of environmental factors conditions.
2.2 coloring capability
Lycopene as a natural red pigment, how to keep its strongest tinting strength is critical. The tomato Lycopene exist in two states: most of them are slender, needle-like crystals form in the colored body, showing bright red. When the crystallization of the lycopene, plastid membrane disappears, the pigment dispersed in the protoplasm free crystal, observed under the microscope, you can see a small colored granular body, indicating the apparent color of color bodies; another fraction (about 10%) the formation of complexes with proteins present in the cell. Lycopene is present in different forms with different color and intensity, but also as the solvent and the different media presents a different color. For example, dissolved in petroleum ether lycopene yellow, then red in carbon disulfide.
2.3 Solubility
Lycopene is a fat-soluble dye, other lipid soluble and non-polar solvents, insoluble in water, soluble in polar solvents such as methanol, ethanol and the like, soluble in aliphatic hydrocarbons, aromatic hydrocarbons and chlorinated hydrocarbons such as ethane, benzene, chloroform and other organic solvents. Lycopene solubility in various solvents increases as the temperature rises, however, the more pure the sample, dissolve more difficult. Slowly dissolve lycopene crystals, tend to form a super-saturation, while increasing the temperature to accelerate the dissolution, the cooling crystallization may occur, then can use ultrasonic waves accelerate dissolution. Although pure lycopene is insoluble in water, but when it is combined with certain substances, such as proteins form complexes, then a high solubility.

More about:natural emulsified lycopene for sale
From:Natural Food Colors

What is Lutein?



Basic concepts:

Lutein is a widely present in vegetables, flowers, fruits and other natural substances in plants, living in "carotenoid class" family matter, now known in nature there is more than 600 carotenoids of which only about 20 species present in the human blood and tissues. Found in humans carotenoids include α-carotene, β a carrot category, cryptoxanthin, lutein, lycopene, and are not flavin. Medical experiments prove that the plant contains natural lutein is an excellent anti-oxidant in food by adding a certain amount of lutein can prevent cell aging and the aging body organs, but also the prevention of age-related macular degeneration eye vision loss and blindness caused by a series of medical studies, carotenoids have been proposed as a cancer preventive agent, life extension agents, ulcers resist agent, heart attack and coronary artery disease resist agent. Meanwhile, lutein can be used as feed additives for poultry meat and eggs coloring, but also in the food industry as a coloring agent and nutritional health.
Lutein is a human daily consumption of fruits and vegetables can be absorbed into nutrients. If the lack of lutein may be taking supplements. If you have poor digestive system of the elderly, sublingual sprays can be used to supplement lutein. As early as 1996 lutein has been added to dietary supplements. In addition, lutein may cause liver absorb excess excess burden of the daily recommended dosage is about 6 mg. No human studies have shown that consumption of lutein can prevent eye diseases, eye diseases prevention really need to rely on a regular basis to avoid excessive use of the eyes and the eyes to rest, before eating lutein consultation with an ophthalmologist.

Differences:

Still unknown lutein and lutein ester functional differences between. It has been reported that lutein esters low bioavailability. A variety of green leafy vegetables such as spinach, mustard greens, lettuce, broccoli, melon, radish, corn and so contains a very large amount of lutein, normal balanced diet supplements can be taken more than the amount.

Lutein effects:

Lutein is an important antioxidant, the carotenoid family (group of plants found in the natural fat-soluble pigments), a member, known as "plant progesterone", zeaxanthin in nature co-exist with .
⑴ main retinal pigment ingredient: Lutein and zeaxanthin constitutes vegetables, fruits, flowers and other plant pigments main component, but also the human retinal macular area * main pigment. The human eye contains high levels of lutein, this element can not be manufactured by the body and must be supplemented by the intake of lutein, if the lack of this element, the eyes will blindness.
⑵ protect your eyes from light damage, slow aging and prevent eye disease: the sun's UV rays and blue light entering the eye will produce a large number of free radicals, leading to cataracts, macular degeneration, and even cancer. Cornea and lens UV generally be filtered out, but they can penetrate the eye directly to Blu-ray and macular retina, macula lutein is able to filter out blue light, blue light to avoid damage to the eyes. Outer macular region particularly vulnerable to fat oxidation sun damage, so this area prone to degradation.
⑶ antioxidant that helps prevent aging body caused by cardiovascular sclerosis, coronary heart disease and cancer diseases.
⑷ protect eyesight: lutein as an antioxidant and photoprotective effect, can promote retinal cells rhodopsin (Rhodopsin) re-generation, can prevent severe myopia and retinal detachment, and can improve vision, protect eyesight. Particularly suitable for students, drivers, and human consumption.
⑸ relieve the symptoms of fatigue; (blurred vision, dry eyes, eye swelling, eye pain, photophobia, etc.)
⑹ increase macular pigment density, protecting the macula, macular promote development;
⑺ prevent macular degeneration and retinitis pigmentosa;
⑻ reduce the generation of drusen to prevent the occurrence of AMD;

Lutein effect:

Protect eyesight
Lutein in the macula of the retina has an important protective role, the lack of easily cause macular degeneration and blurred vision. Further deterioration in visual acuity, myopia and other symptoms. Lutein is the precursor of VA in the human body can be converted to VA. Lutein for the eyes of the main physiological function is to act as antioxidants and light protection. Optic non-renewable, highly vulnerable to harmful free radical damage, antioxidant lutein can inhibit the formation of harmful free radicals. Lutein can absorb a large number of blue, blue wavelengths of visible light and ultraviolet light close to the visible light can reach the retina in a light most potentially harmful. In sensitive cells on the retina before the light go through the highest lutein gathering area, then if, as the macula lutein-rich will be able to minimize such damage.
The role of antioxidant

Lutein has strong antioxidant, can inhibit the activity of ROS, reactive oxygen species to prevent damage to normal cells. For experiments show that reactive oxygen species with DNA, proteins, lipids react undercut their physiological functions, and thus cause such as cancer, arteriosclerosis, degeneration of aging in chronic diseases such as yellow magic place. Lutein can be quenched by physical or chemical inactivation of the role of singlet oxygen, thereby protecting the body from injury, enhance the body immunity.
Reduce the incidence of cataracts

Cataracts are the leading cause of blindness worldwide major eye diseases, the latest studies have shown that by increasing the intake of lutein can achieve the purpose of birth rate, currently considered the mechanism to lower macular pigment density and higher in the elderly lens closely related to the visual density, and the higher density of the lens is considered to be visually obvious features of cataract.
Retard atherosclerosis effect

Recent research results show that lutein on early atherosclerosis process has delayed effect. Main trunk artery intima-media thickness changes in blood relationship between lutein content. Low levels of lutein in the blood, can easily cause arterial wall thickening, with lutein content increased gradually reduced tendency to arterial wall thickening, arterial thrombosis was also significantly reduced. Meanwhile, the leaf cells of the arterial wall can reduce the yellow index of LDL cholesterol oxidation.
Anticancer


Lutein:

Several studies have shown that lutein can inhibit a variety of cancers, such as breast cancer, prostate cancer, colorectal cancer, skin cancer. According to a recent New York University School of drugs in reducing the incidence of breast cancer and lutein intake has a very close relationship between the survey found that lutein intake experimental group with low incidence of breast cancer is the intake high levels of group (2.08 - 2.21) times. This effect may involve coordination with other organs indirect immune regulation. The study concluded that the dietary intake of lutein can not only inhibit neoplasms can even play a preventive role in tumorigenesis. Relevant agencies recommended daily intake per capita 400 g ~ 600 g of fruits and vegetables can make the relative risk of cancer by 50%.

The role of retinal degeneration
Retinitis pigmentosa (RP) is a chronic, progressive, hereditary, malnutrition, Retinitis Pigmentosa. Early symptoms of night blindness RP only and do not affect the work, like night blindness often appears in childhood, as the disease progresses, the dark suitable capacity degradation, photophobia, vision quietly dropped, reduced vision, and finally tubular vision and blindness, is called "not cancer cancer." RP including retinitis pigmentosa, crystalline retinitis pigmentosa, retinitis pigmentosa white spots and non-pigmented retinitis pigmentosa. RP lesions mainly neurosensory retina, especially those responsible for the dark light rod cells for vision degeneration, night blindness, followed by progressive retinal atrophy from outer to inner layers of tissue, associated gliosis. RPE degeneration and hyperplasia also occurred, visible depigmentation or accumulation of migration to the inner retina. Retinal vascular wall thickening occurs hyaline degeneration and even complete occlusion of the lumen. Can have different degrees of choroidal sclerosis, complete or partial disappearance of capillaries. Atrophy of the optic nerve can be completely, depending on the ribs often gliosis, forming membrane block, and retinal glial membrane connected inside. Harvard Eye disease case management team age-related macular degeneration (AMD) and retinitis pigmentosa (RP) and the relationship between the intake of lutein been studied, patients were divided into three groups, respectively, daily intake 30mg, 10mg , 3mg less lutein. Lutein 30mg daily intake of 140 days had, retinal pigment average increase of 20 to 40%, age-related macular degeneration (AMD) and retinitis pigmentosa (RP) lesions were significantly increased visual acuity. The intake of 30mg group and 3mg following group, the two groups differ cure rate of 86%. Visible, lutein supplementation can increase the retinal pigment density, improve vision in patients with RP, the RP to improve treatment rates.
Prevention retinopathy

Diabetic retinopathy is caused by the invasion of hyperglycemia long eye retinal capillary circulation disorders: stagnant blood flow, tissue hypoxia, brittle capillary wall degeneration, retinal posterior pole retinal capillary hemangioma appears, point-like or sheet spotting, cotton wool exudate, causing vision loss. If not treated in time, the lesions will be further developed. Retina of the eye due to lack of oxygen produce new blood vessels, can cause vitreous hemorrhage, reproduction retinopathy, traction retinal detachment, secondary glaucoma, leading to blindness. Lutein, zeaxanthin can significantly improve vascular resistance and restore the balance of blood osmotic pressure loss, decrease vascular permeability, inhibit vascular leakage of material, to ensure the integrity of the eye blood vessels, so that the eye receive adequate blood supply . And eyes and can prevent free radical damage to the collagen binding protein, collagen structure to enhance the retina, thereby improving various retinal diseases (such as: diabetic retinopathy, retinitis pigmentation, hemorrhagic and hypertensive retinopathy, macular degeneration and the like) treatment rates, improved recovery therefore lead to loss of vision.


More about:natural Lutein for sale
From: Natural Food Colors


Sunday, June 16, 2013

The function of Anti-PP2Ac

Anti-PP2Ac usually refers to the hydrolysis catalytic enzymes are collectively phosphate compound, or the hydrolysis of poly-phosphate, phosphoric acerbic admixture enzymes in general. Sometimes aswell referred to as polyphosphoric acerbic phosphatase enzymes and enzymes. The above mainly includes Phosphomonoesterase phosphodiesterase blazon and class. The closing has adenosine triphosphatase, pyrophosphatase, fractional phosphatase. Phosphatase is a way to accord to the phosphorylation of the substrate of the enzyme, i.e. by hydrolyzing the substrate phosphate monoester phosphate accumulation on the atom removed and generates phosphate ions and chargeless hydroxyl groups. The role of phosphatases and kinases contrary, phosphorylase kinase, can use the activity molecule, such as ATP, phosphate groups to accord to the substrate molecule. Are accepted in abounding bacilli is an acrid phosphatase. Phosphatases can be disconnected into two categories: cysteine-dependent phosphatase phosphatase and metals (in its activity depends on the alive website of the metal ion). First, the agitator alive website cysteine ​​on the abandon of nucleophilic groups advancing the phosphate accumulation of the phosphorus atom and bonding; Then, affix the phosphate accumulation and Tyrosine PO key to acquire the position of a acceptable acerb amino acids ( such as aspartic acid) or baptize molecules to accommodate protons protonated, thereby basic phosphoric acerbic - cysteine ​​intermediate; this average was anatomize added baptize molecules, the alive website of the agitator is appear and Proceed to the next dephosphorylation. Metal phosphatase alive website of a aggregate of two catalytic metal ions necessary. As for the attributes of these two metal ions allegation are not consistent, so far not yet conclusive.

Anti-PP2Ac with phosphorylase kinase or phosphorylation of the opposite. Phosphorylation can accomplish an agitator to be activated or deactivated, it can accomplish a protein - protein interactions (such as an SH3 domain); accordingly phosphatase abounding arresting transduction pathways appropriate for ascendancy of phosphorylation. It is account advertence that, phosphorylation or dephosphorylation do not necessarily accord to the activation or inhibition of the enzyme, and some enzymes accept assorted phosphorylation sites complex in the activation or inhibition of the regulation. For example, cyclin-dependent kinase (CDK) to be added than one specific phosphorylated amino acerbic residues, and the agnate activation or inhibition of phosphorylation of altered residues. The acumen phosphate signaling is important for the acumen that it can its bounden proteins that adapt the actions; phosphoric acerbic is removed, it is a about-face activity (if activated by phosphorylation, dephosphorylation is to arrest the effect), phosphatase actuality played an important role. The role of protein phosphatases and protein kinases opposite. According to dephosphorylation of altered amino acerbic residues, is aswell disconnected into protein phosphatase protein tyrosine phosphatase (PTP, PTPase) and serine / threonine phosphatases. Complex in lymphocyte activation of protein phosphatases are: ① CD45: The atomic anatomy of the intracellular domains of the two segments to play the role of PTP, and appropriately accord to CD45 receptor-type protein tyrosine phosphatase, beat kPTK role in the action adjoin aqueous and startup cellular arresting transduction plays a key role; ② calcineurin (calcineurin) is a serine / threonine phosphatase, its substrate is the archetype agency NF-AT atom has occurred phosphorylated serine and threonine residues. Calcineurin in the role, NF-ATp due to abatement of phosphate (p) and the activation, a archetype agency activating NF-AT.

more about: buy Anti-PP2Ac

from: Elisa assay kits