Methylcobalamin is a cobalamin (MeCbl or MeB12) used in the treatment of peripheral neuropathy, diabetic neuropathy, and as a preliminary treatment for amyotrophic lateral sclerosis. It is a form of vitamin B12 and differs from cyanocobalamin in that the cyanide is replaced by a methyl group. Methylcobalamin has been deliberate incoming conjunctive with sleep-wake rhythm method perturbs, where it appears to yield benefits, but at a low or inconsistent level.
It is used in treating diseases of vitamin B12 deficiency (so much as malignant anemia), or diseases of effective B12 inadequacy, such as antipernicious anemia factor metabolic nerve pathway pathologies.
One study suggests that in one case engulfed, methylcobalamin possibly held back inwards the body better than cobalamin. Methylcobalamin is a cobalamin (MeB12) habituated incoming peripheral neuropathy, diabetic neuropathy etc. It is a form of vitamin B12. This vitamer is one of two active coenzymes used by B-12 dependent enzymes in the body, and is specifically the B-12 form used by 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), also recognised as methionine synthase.
The rationale is that methylcobalamin may help to remove brain-damaging levels of the neurotransmitter glutamate. Methylcobalamin has been reported to have been used to reduce neurotoxicity and lower excess glutamate levels, resulting in the reduction of fatigue, stabilisation of mood, improvement of memory, and executive function. However, clinical trials using methylcobalamin have been small and, for the most part, have not been replicated or confirmed.
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