Uses of Phosphomannomutase PMM2 Monoclonal Antibody 2E9

Phosphomannomutase PMM2 Monoclonal Antibody 2E9 encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a forerunner to GDP-mannose all-important for the amalgam of dolichol-P-oligosaccharides. Mutations in this gene accept been apparent to could cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein affection blazon I.
In enzymology, a phosphomannomutase (EC 5.4.2.8) is an agitator that catalyzes the actinic reaction
alpha-D-mannose 1-phosphate rightleftharpoons D-mannose 6-phosphate
Hence, this agitator has one substrate, alpha-D-mannose 1-phosphate, and one product, D-mannose 6-phosphate.
This agitator belongs to the ancestors of isomerases, accurately the phosphotransferases (phosphomutases), which alteration phosphate groups aural a molecule. The analytical name of this agitator chic is alpha-D-mannose 1,6-phosphomutase. Other names in accepted use cover mannose phosphomutase, phosphomannose mutase, and D-mannose 1,6-phosphomutase. This agitator participates in fructose and mannose metabolism. It has 2 cofactors: D-glucose 1,6-bisphosphate, and D-Mannose 1,6-bisphosphate.
Uses of Phosphomannomutase PMM2 Monoclonal Antibody 2E9
Antibody reactive against transfected lysate and recombinant protein for Western Blot. Has also been used for ELISA.
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