Tuesday, March 13, 2012

What is GFAP (phospho-Ser8) Monoclonal Antibody (YC10)?

GFAP (phospho-Ser8) Monoclonal Antibody (YC10)
Specification:50 µg 
Purification:Protein A Affinity
Immunogen:Synthetic phospho-peptide derived from the sequence of pig GFAP, conjugated to KLH
Storage pH: 7.20
Constituents: 49% PBS, 50% Glycerol
Description of GFAP (phospho-Ser8) Monoclonal Antibody (YC10)
Glial Fibrillary Acidic Protein (GFAP) is an intermediate-filament (IF) protein that is specific for cells of astroglial lineage. The major IF protein expressed in precurosor astrocytes in the CNS is usually vimentin. A switch between vimentin and GFAP expression occurs following astrocyte maturation, making GFAP a widely used marker for astrocyte maturation. GFAP expression is modulated by several hormones including thyroid hormone, glucocorticoids and several growth factors such as FGF, CNTF, and TGF-beta.
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